منابع مشابه
Inotropic action of hexamethonium.
The positive inotropic action of hexainethoniuin in hypodynamic and freshly prepared papillary muscles of the cat and the hypodynamic heart-lung preparation of the dog has been demonstrated. Within certain limits, there exists a proportionality between the concentration of hexamethonium and the magnitude of the inotropic response. In both preparations results have been obtained which indicate t...
متن کاملHexamethonium and glaucoma.
THIS investigation was undertaken in an endeavour to decide if the methonium ganglion blocking compounds could be administered to cases of vascular hypertension who were known to be suffering from glaucoma, or to similar vascular hypertensive cases of a glaucomatous disposition although this might not be known, without the danger of subsequent sequelae such as an increase in intra-ocular pressu...
متن کاملLung changes during hexamethonium therapy for hypertension.
During the course of treating 54 severely hypertensive patients with parenteral hexamethonium bromide, wehave observed the development of unexpected pulmonary dyspnea and associated radiographic changes in the lungs in three cases after 7, 9, and 12 months' therapy respectively. Two of these came to autopsy; the third has recovered. The object of this paper is to record the clinical, radiologic...
متن کاملThe treatment of hypertension with hexamethonium.
Hexamethonium by subcutaneous injection in doses of 10 to 75 mg. of the ion every 8 or 12 hours produced significant reductions of arterial pressure and symptomatic improvement in a high percentage of patients with benign or malignant hypertension. Methods for preventing tolerance and undesirable side effects are presented, and the advantages as well as the limitations of hexamethonium therapy ...
متن کاملHexamethonium in the Chronic Treatment of Hyper-
Neurogenic (autonomic) factors in hypertensive vascular disease (1, 2) may be studied with hexamethonium 2 which reduces arterial blood pressure by blockade of the sympathetic ganglia. When the blood pressure is reduced acutely in this manner, alterations in renal hemodynamics have been observed. Following a single dose of hexamethonium administered parenterally to patients with hypertension, t...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1982
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.1982.tb01331.x